"The Old Curiosity Shop" by Charles Dickens is a novel published serially from 1840 to 1841. The story follows young Nell Trent and her grandfather, who are driven from their London shop by an evil moneylender after the grandfather's gambling debts spiral out of control. The pair flee to the English Midlands as beggars, pursued by various parties with different motives. This tale of virtue, villainy, and sacrifice became so popular that New York readers reportedly stormed the docks awaiting its final installment.
Wikipedia page about this book: en.wikipedia.org/wiki/The_Old_Curiosity_Shop